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Obesity-Hypoventilation Syndrome - A term applied to obese individuals who have abnormally slow and shallow respiration (hypoventilation) during wakefulness, resulting in an increased level of carbon dioxide in the blood. Obstructive Hypopnea - Periodic, partial closure of the throat during sleep resulting in reduced air exchange. The medical consequences of this partial closure can be as severe as sleep apnea (full closure of throat) Usually characterized by snoring, excessive daytime sleepiness, and other symptoms of fatigue Obstructive Sleep Apnea - Repetitive cessation of breathing during sleep for 10 seconds or more due to complete closure (collapse) of the throat. Usually characterized by snoring, excessive daytime sleepiness, and other symptoms of fatigue. Ondine's Curse - Condition in which the respiratory center in the brain is unable to stimulate breathing in response to an increased amount of carbon dioxide in the blood. Ondine's Curse is synonymous with central alveolar hypoventilation and typically worsens during sleep. Optimum Sleep - The average amount of sleep needed every night by any given individual. Most adults require about 7 to 8.5 hours per night, although this number is subjective, and may vary from person to person. Oscillograph - A device that displays ongoing physiological patterns (EEG) or other variables usually tracing on moving paper or a CRT screen. Oxygen Desaturation - Less than normal amount of oxygen carried by hemoglobin in the blood. A value below 90% is considered abnormal. Oxygen Saturation - A measure of oxygen carried by hemoglobin in the blood. Normal values range from 90% to 100%. An important indicator of sleep disordered breathingthat is directly affected by the degree of throat closure (partial vs. complete) and its duration. Oxygen saturation is recorded in both diagnostic sleep studies and titration studies. Oximeter - Medical device used to provide estimates of arterial oxygen saturation (SaO2) by utilizing selected wavelengths of light to noninvasively determine the saturation of oxyhemoglobin (SpO2). Oximetry - Test used to continuously monitor the oxygen saturation of arterial blood from a pulse oximeter sensor attached to the finger.
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